5-Hydroxyindoleacetic acid, 24h urine

Test Name
5-Hydroxyindoleacetic acid, 24h urine
Aliases
5-HIAA, serotonin metabolite
Provincial Mnemonic
HI5U24HD
LOINC Test Code
14573-0
Description and Primary Use
5-HIAA is measured in urine for diagnosis investigation and/or monitoring of carcinoid tumor.
Reorder interval
Not yet defined
TAT
14 d
Test Cost
Not Available
Tier
1 - General Availability
Ordering Requirements (Restrictions / Conditions)

Enter test name (and/or Provincial Mnemonic) into Additional Requests section on the outpatient requisition form.

Required Consultations
None
Algorithms and Guidelines

None

Special Patient Preparation

Patient dietary restrictions required. [Add link to patient preparation  PDF]

Special Collection / Transport / Processing Requirements

24 hour urine collection – 24 hour collection bottle with 25 ml of 6N HCL. Upon lab reception the pH shall be in between 1-5. If the specimen was refrigerated during the collection and is not older than 12 hours after the end of the collection, the pH can be adjusted to 1-5 with 6N HCl. Otherwise, reject the specimen. Aliquot 3 samples with roughly 10 ml in each and freeze at -20ºC as soon as possible. Enter in the LIS the Start and End Date & Time of the urine collection, the final pH and the total urine volume collected.

Criteria for Rejection

Based on specimen condition and stability; Thawed sample (Thawed prior to receipt in Mass Spec Lab).

Laboratory Service Area
Clinical Chemistry
Performing Laboratory / Site
Category 4 Laboratory (HSC only)
Last Updated
19-Aug-19