Free cortisol, 24h urine

Test Name
Free cortisol, 24h urine
Aliases
CUF; UFC; Urinary free cortisol
Provincial Mnemonic
COFU24HD
LOINC Test Code
14676-1
Description and Primary Use
A sensitive test for various types of adrenocortical dysfunction, particularly hypercortisolism (Cushings Syndrome), apparent mineralocorticoid excess, and congenital adrenal hyperplasia.
Reorder interval
Not yet defined
TAT
14 Days
Test Cost
Not Available
Tier
1 - General Availability
Ordering Requirements (Restrictions / Conditions)

No Restrictions

Required Consultations
None
Algorithms and Guidelines

None

Special Patient Preparation

None

Special Collection / Transport / Processing Requirements

24 hour urine collection bottle should contain 25 ml of 50 % Acetic Acid as preservative. Another acceptable preservative is 10 g of boric acid or no preservative if sample kept refrigerated. Aliquot 2 samples of roughly 10 ml each and freeze at -20oC as soon as possible. Enter Start and End Dates & Times of urine collection and total urine volume into LIS.

Criteria for Rejection

Based on specimen condition and stability; Random urine, Unrefrigerated sample,  Thawed sample (Thawed prior to receipt in Mass Spec Lab);  24 hour total volume not provided.

Laboratory Service Area
Clinical Chemistry
Performing Laboratory / Site
Category 4 Laboratory (HSC only)
Last Updated
04-Sep-19