- Test Name
- GBM Autoantibody, Quantitative
- Aliases
- Anti-GBM; Glomerular Basement Memberane Autoantibody
- Provincial Mnemonic
- GLBMAB
- LOINC Test Code
- 59394-7
- Description and Primary Use
- Quantitative GBM autoantibody referred out testing is only performed when the qualitative test of the GVDS panel have reported positivity for the GBM autoantibody. The diagnosis of Goodpasture’s disease relies on the detection of GBM autoantibodies in tissues or circulation in combination with the detection of glomerulonephritis and/or alveolitis. GBM autoantibodies are highly specific and sensitive markers of the disease and are by definition present in all patients with Goodpasture’s disease. Clinical progression of the disease correlates with antibody concentrations, with high concentrations of circulating GBM autoantibodies indicating an unfavorable prognosis.
- Reorder interval
- 30d
- TAT
- 14 Days; max delay 31 days.
- Test Cost
- Not Available
- Tier
- 2 - Conditional/Restricted Access (See Ordering Requirements)
- Ordering Requirements (Restrictions / Conditions)
Quantitative GBM autoantibody is only performed when the qualitative test of the GVDS panel have reported positivity for the GBM autoantibody.
Approval requires:
- Ordered by Rheumatology
- Completed LTSA Form.
Enter test name (and/or Provincial Mnemonic) into Test(s) to be performed section on the LTSA Form. Direct questions on how to order test to Specimen Dispatch (709-777-2373).
- Required Consultations
- Algorithms and Guidelines
- Special Patient Preparation
None
- Special Collection / Transport / Processing Requirements
No special requirement
- Criteria for Rejection
Please consult specimen stability guide
- Laboratory Service Area
- Clinical Chemistry
- Performing Laboratory / Site
- Category 4 Laboratory (HSC only)
- Last Updated
- 04-Sep-19