- Test Name
- LH
- Aliases
- Luteinizing Hormone
- Provincial Mnemonic
- LH
- LOINC Test Code
- 10501-5
- Description and Primary Use
- LH, together with FSH, is secreted by the gonadotroph cells in the pituitary in response to the secretion of the gonadotropin releasing hormone (LHRH, GnRH) from the medial basal hyporthalamus. Ovarian steroids, principally estrogens, modulate the secretion of LH and FSH which in turn regulate the menstrual cycle in females. When the follicle and the ovum contained within it, reaches maturity, a surge of LH causes the folllicle to rupture releasing the ovum. The follicular remnant is transformed into a corpus luteum, which secretes progesterone and estradiol. During the follicular and luteal phases, LH concentrations are much lower than the levels observed at the time of the LH surge. During the follicular and luteal phases, the estrogens exert a negative feedback on the release of LH. Shortly before the mid-cycle surge in LH, ovarian steroids, specifically estradoil, exert a positive feedback on the release of LH.
- Reorder interval
- Not yet defined
- TAT
- ≤3 Days
- Test Cost
- Not Available
- Tier
- 1 - General Availability
- Ordering Requirements (Restrictions / Conditions)
No Restrictions
- Required Consultations
- None
- Algorithms and Guidelines
None
- Special Patient Preparation
None
- Special Collection / Transport / Processing Requirements
No special requirement
- Criteria for Rejection
Grossly hemolyzed samples (>5.0g/L hemoglobin.)
- Laboratory Service Area
- Clinical Chemistry
- Performing Laboratory / Site
- Category 4 Laboratory (HSC only)
- Last Updated
- 04-Sep-19