- Test Name
- Sirolimus trough, whole blood
- Aliases
- Sirolimus trough level; Rapamycin; Sirolimus; Siro
- Provincial Mnemonic
- SIRTR
- LOINC Test Code
- 29247-4
- Description and Primary Use
- Monitoring whole blood sirolimus concentration during therapy, adjusting dose to optimize immunosuppression while minimizing toxicity, evaluating patient compliance.
- Reorder interval
- Not yet defined
- TAT
- 5 Days
- Test Cost
- Not Available
- Tier
- 1 - General Availability
- Ordering Requirements (Restrictions / Conditions)
No Restrictions
- Required Consultations
- None
- Algorithms and Guidelines
None
- Special Patient Preparation
None
- Special Collection / Transport / Processing Requirements
Sample should be kept as whole blood in original collection container. Collect in a lavender top (EDTA) tube, minimum 3 mL. Mix the whole blood but do not centrifuge the tube. Collect whole blood trough level sample immediately before the next scheduled dose. Provide the date and time of the collection and of the next scheduled dose. Store refrigerated or frozen for up to 14d.
- Criteria for Rejection
Based on specimen condition and stability
- Laboratory Service Area
- Clinical Chemistry
- Performing Laboratory / Site
- Category 4 Laboratory (HSC only)
- Last Updated
- 18-Sep-19