Urinary Free Cortisol

Test Name
Urinary Free Cortisol
Aliases
Free Urinary Cortisol
Provincial Mnemonic
COFPU24H
LOINC Test Code
43126-2
Description and Primary Use
Sensitive test for various types of adrenocortical dysfunction, particularly hypercortisolism (Cushings Syndrome), apparent mineralocorticoid excess and congenital adrenal hyperplasia.
Reorder interval
Not yet defined
TAT
Not yet defined
Test Cost
Not Available
Tier
1 - General Availability
Ordering Requirements (Restrictions / Conditions)

No Restrictions

Required Consultations
None
Algorithms and Guidelines

None

Special Patient Preparation

None

Special Collection / Transport / Processing Requirements

24hr urine collection with 25mL 50% Acetic Acid. Adjust pH to be less than 4. Freeze two 10-15mL aliquots. Other acceptable specimens are 24hr urine with 25 mL 6N HCl, 24hr urine with 10g Boric Acid, or 24hr urine with no preservative. State total volume and pH on label

Criteria for Rejection

Avoid Freeze and thaw cycles, If NO total 24hr volume provided.

Laboratory Service Area
Clinical Chemistry
Performing Laboratory / Site
Category 4 Laboratory (HSC only)
Last Updated
19-Sep-19